Miss Fortune joins Gangplank among the pirate champions of LoL, but after playing her, I feel like that cowgirl skin should be her default. Not only is it the hottest of the three skins, but she has a run-and-gun feel to her that makes me think of games like Sunset Riders. She’s a ton of fun to play, but that may be because she is so strong.
If you were ever into Gangplank, you’ll probably find Miss Fortune really enjoyable. She has all the great things about him – a cannon ball slow, a “wtf just hit me” shot, anti-healing, a fun ult, and very high move speed – and she has the added benefit of farming from range. She doesn’t have his free cleanse, but her range and her passive more than make up for it.
As far as build goes, it seems like AD is the way to be. I’ve personally been starting with Manamune and moving straight to Infinity because her farm is nearly unstoppable. Bloodthirster is also a good rush item, though I think you’ll realize how much she needs mana early on. The key, though, is keeping up that farm. With her movespeed you should always be near creeps, always last hitting everything you can see.
As far as playing against her, you better bring a lot of stuns. Because she has no inherent escape mechanism, I think you’ll see a lot of Miss Fortune players running Flash/Ghost for summoner skills, which means you need to lock her down fast. As a mid player, you may want to think about taking a cloth armor first with a bunch of health pots. It will mitigate some of her Double Up damage, which is where she gets most of her harass, and force her to use more mana to get you as low as she’d like, which means she won’t have tons of mana for that big ult. If you’re playing a carry, Flash is almost a must. Her ult hits so hard so fast that you need to get out of there within a half second. With a minimal farm she can hit you for 800 damage at level 16, which is a LOT on a carry. Add in a 300-400 damage Double Up and you’re looking at some fountain time.
I would not be surprised to see her nerfed next patch. Despite some of the posts in the forums calling her “useless” and “way underpowered,” she has that mix of magic and physical damage that both scale off of her attack damage. It allows her to provide a heavy mix of damage that is very difficult to build against. I would love to see Riot introduce another hybrid mitigation item like Aegis of the Legion. Players need an item to help against toons like Ezreal, Miss Fortune, and even Kog’Maw, who can all provide a mix of damage in huge waves.